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The association between third trimester multivitamin/mineral supplements and gestational length in uncomplicated pregnancies

  • J.M. McAlpine
    Affiliations
    School of Medical Science, Menzies Health Institute Queensland, Griffith University Gold Coast Campus, Southport, QLD, Australia

    Department of Women's and Newborn Health, Gold Coast University Hospital, Southport, QLD, Australia
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  • R. Scott
    Affiliations
    School of Medicine, Menzies Health Institute Queensland, Griffith University, Gold Coast Campus, Southport, QLD, Australia
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  • P.A. Scuffham
    Affiliations
    School of Medicine, Menzies Health Institute Queensland, Griffith University, Gold Coast Campus, Southport, QLD, Australia
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  • A.V. Perkins
    Affiliations
    School of Medical Science, Menzies Health Institute Queensland, Griffith University Gold Coast Campus, Southport, QLD, Australia
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  • J.J. Vanderlelie
    Correspondence
    Corresponding author at: School of Medical Science, Griffith University Gold Coast Campus, Parklands Drive, Southport, QLD 9726, Australia. Tel.: +61 07 5552 8746.
    Affiliations
    School of Medical Science, Menzies Health Institute Queensland, Griffith University Gold Coast Campus, Southport, QLD, Australia
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Published:August 26, 2015DOI:https://doi.org/10.1016/j.wombi.2015.07.185

      Abstract

      Background

      Widespread use of maternal micronutrient supplements have been correlated to gestational length and outcome in women predisposed to pre-eclampsia and preterm birth. However, research is yet to be conducted examining the influence of micronutrient supplements on outcomes at term in uncomplicated pregnancies.

      Aim

      To analyse the relationship between third trimester micronutrient supplementation and gestation length at birth, demographics and maternal birthing outcomes in well women at term in a South East Queensland representative population.

      Methods

      This research retrospectively analysed existing data pertaining to 427 uncomplicated, pregnancies birthing at the Gold Coast and Logan Hospitals using information gathered through the Environments for Healthy Living Study and Queensland perinatal data collection. Data were analysed using SPSS v20 by Chi square, ANOVA and regression analysis.

      Findings

      Women in the third trimester taking individual zinc, folic acid or iron supplements in combination with a multivitamin were twice as likely to birth beyond 41 completed weeks (AOR 2.054, 95% CI 1.310–7.383, p = 0.038) then those who did not take any supplement when controlled for established confounders. Non supplement users were found to experience a lower rate of post dates labour and requirements for induction (AOR 0.483, 95% CI 0.278–0.840, p = 0.01).

      Conclusion

      Length of gestation demonstrates significant associations with micronutrient supplementation practices. Well women consuming third trimester individual micronutrient supplements in addition to multivitamins experienced a longer gestation at term compared to women taking no micronutrients, increasing their risk for postdates induction of labour.

      Keywords

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